Statins, Central Blood Pressure, and Blood Pressure Amplification

Statins, central blood pressure, and blood pressure amplification.

It is well established that blood pressure (BP) differs markedly between peripheral (brachial) and central arteries (aorta).1 As the pressure wave travels distally from the heart, mean BP and diastolic BP decrease slightly (1 to 2 mm Hg), but a gradual and significant increase of systolic BP (SBP) and pulse pressure (PP) occurs. This phenomenon is called BP amplification.1 The development of co...

Use of statins and blood pressure.

BACKGROUND Markers of inflammation such as high-sensitivity C-reactive protein (CRP) were shown to be elevated in patients with hypertension. Small trials using statin therapy showed blood-pressure (BP) reductions, but it is unknown whether this association extends to larger populations. The objective of this study was to determine whether statin use was associated with better blood-pressure co...

Central blood pressure and hypertension.

During the 20th century, the brachial artery auscultatory method of blood pressure (BP) measurement has been the major basis for our understanding of clinical hypertension. First, the height of systolic (S) and diastolic (D) BP was used to define cardiovascular (CV) risk. Second, BP reduction by drug treatment was shown to be associated with a substantial decrease of CV risk in several varietie...

Comparison of Various Blood Pressure Measurement Techniques with Standard Office Based Blood Pressure Mesurement

Introduction: In order to control Hypertension, it is necessary to understand the methods of blood pressure measurement. Recent guidelines emphasize on employing appropriate blood pressure measurement techniques and white coat hypertension. Definition and methods of blood pressure measurement have changed in the American guideline based on SPRINT trial (Systolic Blood Pressure Intervention Tria...

Blood and Blood-Pressure